Medications are all poisonous but did you know some cause weight gain?
Are you a victim of a very nasty side effect of a medication meant to help you?
Tricyclic antidepressants, also known as cyclic antidepressants or TCAs, may cause weight gain.
- amitriptyline (Elavil)
- amoxapine
- desipramine (Norpramin)
- doxepin (Adapin)
- imipramine (Tofranil-PM)
- nortriptyline (Pamelor)
- protriptyline (Vivactil)
- trimipramine (Surmontil)
Monoamine oxidase inhibitors (MAOIs) were the first class of antidepressants to be developed. MAOIs that cause weight gain include:
- phenelzine (Nardil)
- isocarboxazid (Marplan)
- tranylcypromine (Parnate)
SSRIs are the most commonly prescribed class of depression drugs. Long-term use of the following SSRIs may cause weight gain:
- paroxetine (Paxil, Pexeva, Brisdelle)
- sertraline (Zoloft)
- fluoxetine (Prozac)
- citalopram (Celexa)
Mirtazapine is less likely to make people gain weight compared with TCAs.
It also doesn’t result in as many other side effects as other antidepressants. However, it can cause:
- nausea
- vomiting
- sexual dysfunction
Other antidepressants have been associated with less weight gain as a side effect. These antidepressants include:
- escitalopram (Lexapro, Cipralex), an SSRI
- duloxetine (Cymbalta), a serotonin-norepinephrine reuptake inhibitor (SNRI), may cause modest weight gain with long-term use
- bupropion (Wellbutrin, Forfivo, and Aplenzin), an atypical antidepressant
- nefazodone (Serzone), a serotonin antagonist and reuptake inhibitor
- venlafaxine (Effexor) and venlafaxine ER (Effexor XR), which are both SNRIs
- desvenlafaxine (Pristiq), an SNRI
- levomilnacipran (Fetzima), an SNRI
- vilazodone (Viibryd), a serotonergic antidepressant
- vortioxetine (Trintellix), an atypical antidepressant
- selegiline (Emsam), a newer MAOI that you apply to your skin, which may lead to fewer side effects than MAOIs taken by mouth
Weight gain is also less likely to occur with the following SSRIs when they’re used for less than six months:
- sertraline (Zoloft)
- fluoxetine (Prozac)
- citalopram (Celexa)
Talk with your physician about whether this could be the reason your not able to drop the weight.
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